FK-506 生化試劑現(xiàn)貨7折促銷啦~絕對最低價！

瀏覽次數(shù)：3581　發(fā)布日期：2013-8-13　來源：本站　本站原創(chuàng)，轉(zhuǎn)載請注明出處

產(chǎn)品名稱：FK-506

化學(xué)名：Tacrolimus, fujimycin, Prograf, Advagraf, Protopic

CAS No： 104987-11-3

分子式：C44H69NO12

分子量：804.02

純度：≥99%

溶解度：Soluble in DMSO or ethanol at 100 mg/mL; very poorly soluble in water;

保存：-20 ºC

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貨號：abs810040

規(guī)格：大包裝詢價

貨號產(chǎn)品名稱規(guī)格

abs810040a FK-506 5mg

abs810040b FK-506 10mg

abs810040c FK-506 25mg

abs810040d FK-506 50mg

abs810040e FK-506 100mg

庫存：現(xiàn)貨

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生物活性：

FK-506 is an immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the

activity of the patient's immune system and so lower the risk of organ rejection. It is also used in a topical

preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow

transplants, exacerbations of minimal change disease, and the skin condition vitiligo. It reduces

interleukin-2 (IL-2) production by T-cells.

FK-506 reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP12 (FK506 binding

protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin thus

inhibiting both T-lymphocyte signal transduction and IL-2 transcription.

相關(guān)公司：愛必信（上海）生物科技有限公司
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